News & Updates
  • Added support for official gene symbols (08/25/2014)
  • Fixed a minor bug for dealing with very small datasets (07/15/2014)
  • Improved interface and added a new function for only updating cutoffs (06/04/2014)
  • Fixed a bug for Ensembl ID annotation (03/29/2014)
  • Users can now perform enrichment analysis on genes visually selected from the heatmaps (02/01/2014)
  • Improved heatmap builder (12/12/2013)
  • INVEX official release (09/20/2013)
Please Cite
Xia J, Lyle NH, Mayer ML, Pena OM and Hancock REW (2013) "INVEX - a web-based tool for integrative visualization of expression data" Bioinformatics 29 (24), 3232-3234. (PDF)

Gene expression or metabolomics data generated from clinical studies are often associated with multiple clinical parameters or metadata (i.e. diagnosis, genotype, survival, gender, etc.). It is of great interest to analyze as well as to visualize the data with regard to these metadata. To address this issue, we have developed INVEX - an easy-to-use, highly interactive web-based tool that allows researchers to perform flexible differential expression analysis with regard to different metadata and to visually explore the results within the context of metadata and biological annotations. In addition, INVEX allows users to easily create custom heatmaps from interesting expression patterns and enriched functional categories. INVEX main features:

  • Data annotation for common gene and metabolite IDs;
  • Built-in support for a wide variety of common as well as complex analyses of differential expression;
  • Enrichment analysis to highlight meaningful biological pathways or functional groups;
  • Visual data exploration and pattern discovery by interactive heatmaps;
  • An intuitive heatmap builder for creating custom heatmaps.

design
CIHR Killam UBC
INVEX is being developed by the Hancock Lab at The University of British Columnbia.
Funding is provided by the Killam Trust and the Canadian Institutes of Health Research (CIHR).
For comments and questions, please contact: jeff@hancocklab.com.